OFFICE OF CLINICAL RESEARCH EDUCATION AND COLLABORATION OUTREACH
Bench-to-Bedside and Back Program (BtB)
2021 Bench-to-Bedside and Back Program (BtB) Funded Projects
OFFICE OF CLINICAL RESEARCH BtB FUNDS: Projects Funded by Bench-to Bedside Program Funds
| Project | Institute or Institution Investigators | 
|---|---|
| Molecular Imaging of Multiple Myeloma Targeting BCMA | NCI: Choyke, Peter; Mena, Esther; Young, Ryan NIBIB: Jacobson-Weiss, Orit University of Miami: Landgren, Ola; Kazandjian, Dickran  | 
              
| Endocannabinoid/CB1R system in long-term pulmonary complications of COVID | NIAAA: Resat, Cinar NHGRI: Gochuico, Bernadette Thomas Jefferson University: Summer, Ross  | 
              
| A targeted treatment for the monogenic autoimmune syndrome APECED | NIAID: Lionakis, Michail; Germain, Ronald NIAMS: Nagao, Keisuke; O'Shea, John; Kong, Heidi; NHGRI: Segre, Julie University of California-San Francisco: Anderson, Mark  | 
              
| Plasma EBV DNA based diagnosis of endemic Burkitt Lymphoma in Africa | NCI: Mbulaiteye, Sam; Sampson, Joshua Johns Hopkins University: Ambinder, Richard; Xian, Rena Cancer Genomics Inc: Bhatia, Kishor  | 
              
| Role of Metal Ion Transporter ZIP8 in Alcohol Related Behaviors | NIAAA: Ramchandani, Vijay; Momenan, Reza; Venkatesh,
                  Shyamala; Diazgranados, Nancy University of Pennsylvania: De Biasi, Mariella  | 
              
| Network-based mechanisms of Mindfulness Training for Youth Nicotine Vaping | NIDA: Salmeron, Betty Jo; Yang, Yihong; Curtis, Brenda
                  Lynette; Ross, Thomas Johns Hopkins University: Hammond, Christopher; Sibinga, Erica  | 
              
| Mitochondria-ER contacts in the pathogenesis and therapy of NAFLD | NIEHS: Santos, Janine Thomas Jefferson University: Hajnoczky, Gyorgy  | 
              
| Identification of therapies that block PD-L1 enriched exosome biogenesis | NCATS: Thomas, Craig University of California: Blelloch, Robert  | 
              
| Smart Lung Biopsy with Impedance and Artificial Intelligence | CC: Wood, Bradford; Xu, Sheng; Karanian, John; Pritchard,
                  William NHLBI: Fontana, Joseph University of York: Tse, Zion Rensselaer Polytechnic Institute: Yan, Pingkun  | 
              
| Targeting ER proteostasis to monitor and treat ischemic stroke | NIDA: Harvey, Brandon; Trrychta, Kathleen NCATS: Henderson, Mark The Research Foundation of SUNY: Halterman, Marc  | 
              
| RBC health as a novel biomarker of a successful outcome in HSCT for SCD | NHLBI: Fitzhugh, Courtney Functional Fluidics, Inc: Hines, Patrick; Tarasev, Michael Children's National Medical Center: Campbell, Anderew Foundation for Sickle Cell Disease Research: Bronte-Hall, Lanetta  | 
              
DIETARY SUPPLEMENTS CATEGORY: Project Funded by the Office of Dietary Supplements: (ODS)
| Project | Institute or Institution Investigators | 
|---|---|
| Effect of Nicotinamide Riboside on Ketosis, Fat Oxidation & Metabolic Rate | NIDDK: Hall, Kevin; Rotman, Yaron; Gharib, Ahmed;
                  Courville, Amber; Chen, Kong;  City of Hope: Brenner, Charles  | 
              
MINORITY HEALTH CATEGORY: Project funded by National Institute on Minority Health & Health Disparities (NIMHHD)
| Project | Institute or Institution Investigators | 
|---|---|
| Sleep-time blood pressure and risk of chronic kidney disease progression | NIMHD: El-Toukhy, Sherine University of Texas at Austin: Smolensky, Michael University of Vigo, Spain: Hermida Dominguez, Ramon University of California at Los Angeles: Norris, Keith  | 
              
WOMEN'S HEALTH CATEGORY: Project funded by Office of Research on Women's Health (ORWH)
| Project | Institute or Institution Investigators | 
|---|---|
| A novel osteoporosis treatment targeting the osteoclast surface La protein | NICHD: Chernomordik, Leonid; NIDCR: Collins, Michael  | 
              
Cancer Moonshot Funds-NCI Administrative Supplements
| Project | Institute or Institution Investigators | 
|---|---|
| Alternative splicing of CD22 following Inotuzumab | NCI: Shah, Nirali The Children's Hospital of Philadelphia: Thomas-Tikhoneko, Andrei  | 
              
| B2B and Back: CD22 and CD19/22 CAR immunotherapies for childhood leukemia | NCI: Taylor, Naomi; Altan-Bonnet, Gregoire Yves; Shah,
                  Nirali Stanford University: Mackall, Crystal; Ramakrishna, Sneha  | 
              
| Determinants of pre-mature CAR T cell senescence in B cell cancers | NIA: Weng, Nan-ping University Of Pennsylvania: Fraietta, Joseph; June, Carl  | 
              
| Targeting neuroendocrine tumors with DLK1 directed immunotherapy | NCI: Nitin, Roper; Widemann, Brigitte; Del Rivero,
                  Jaydira The Children's Hospital of Philadelphia: Maris, John; Diskin, Sharon University of Pennsylvania: Amber Weiner  | 
              
| TME informed NK cell therapy for pediatric sarcomas | NCI: Kaplan, Rosandra; Wedekind, Mary Frances; Glod,
                  John; Choyke, Peter; Widemann Brigitte The Research Institute at Nationwide Children's Hospital: Lee, Dean Anthony; Cripe, Timothy  | 
              


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