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OFFICE OF CLINICAL RESEARCH EDUCATION AND COLLABORATION OUTREACH

Bench-to-Bedside and Back Program (BtB)

2005 Bench-to-Bedside and Back Program (BtB) Funded Projects


GENERAL CATEGORY:

Project Institute or institution/Investigators
Induction of volitional swallowing in chronic dysphagia post stroke: A novel mechanism-based intervention NINDS: Ludlow, Christy; Cohen, Leonardo 
NIDCD: Horwitz, Barry
Induction of Mucosal Tolerance to Recombinant Human E-Selectin for the treatment of Myocardial Ischemia-Reperfusion Injury and Symptomatic Coronary Atherosclerosis. A Collaborative NHLBI/NINDS Investigation NHLBI: Desilva, Ranil; Finkel, Toren 
NINDS: Hallenbeck, J.

AIDS CATEGORY:

Project Institute or institution/Investigators
Role of HIV-1 RNase in Developing Resistance to Nucleoside Analogs NCI: Maldarelli, Frank; Pathak, Vinay 
NIAID: Morse, Caryn
Endothelial Dysfunction in HIV-associated Pulmonary Hypertension NHLBI: Machado, R.; Gladwin, M.; Lederman, Robert 
CC: Raghavachari, Nalini; Masur, Henry Other Collaborators: Drs. Barnett, McCoy, Solomon
Clinical Development of E. coli Nissle 1917 as Host for a Live Anti-HIV Microbicide NCI: Hamer, D. 
NIAID: Sereti, Irini Other Collaborators: Drs. Asdhya, Henry, Mannon
Persistent HIV Reservoirs in Infected Patients Receiving Effective Antiviral Therapy for Prolonged Periods of Time: Delineation of the Mechanism and Source of Viral Replication and Execution of a New Therapeutic Strategy NIAID: Chun, Tae-Wook; Moir, Susan; Kottilil, Shyam 
CC: Healey, L.; Kovacs, Joseph

RARE DISEASES CATEGORY:

Project Institute or institution/Investigators
Natural history, biology and treatment of dermal neurofibromas in neurofibromatosis type 1 (NF1) NCI: Widemann, Brigitte 
NHGRI: Stewart, Douglas
Testing Treatment of Hutchinson-Gilford Progeria Syndrome with Farnesyl Transferase Inhibitors NHGRI: Gordon, L.; Gahl, William; Introne, Wendy; Collins, Francis 
NHLBI: Orlic, Donald; Nabel, Elizabeth
Analysis of global gene expression patterns and mitochondrial DNA damage in lymphocytes of Friedreich?s Ataxia patients undergoing idebenone treatment in Phase II double-blind placebo controlled study NIEHS: Van Houten, B.; Haugen, Astrid 
NINDS: Fischbeck, Karen Other Collaborators: Dr. DiProspero
Adoptive Cell Therapy for Ewing?s Sarcoma Using Artificial Antigen Presenting Cells NCI: Mackall, Crystal 
CC: Partners
Ganaxolone Therapy for Niemann-Pick Type C NICHD: Porter, Forbes 
NHGRI: Pavan, William
UVA Sensitivity in Smith-Lemli-Opitz Syndrome: Possible Involvement of Cholesta -5,7,9(11)-trien-3 -ol NIEHS: Chignell, C. 
NICHD: Porter, Forbes
Pre-clinical and clinical investigations into the mechanisms and efficacy of extracorporeal photopheresis (ECP) in the abrogation of graft-vs-host disease (GVHD) and facilitation of graft-vs-tumor (GVT) immunity in pediatric patients CC: Wayne, A.; Leitman, Susan NCI: Fry, Terry; Pavletic, Steven
NIAID: Malech, Harry Other Collaborators: Dr. Bolan
Site-Selective cAMP Analogs for Treatment of Carney Complex NCI: Cho-Chung, Y. 
NICHD: Stratakis, Constantine
Pathogenesis of and risk factors for autoimmunity in the Wiskott-Aldrich Syndrome NIAMS: Siegel, Richard; Nikolov, N 
NHGRI: Candotti, Fabio
Development of a Specific Drug treatment for WHIM Syndrome NIAID: McDermott, David; Murphy, Philip; Malech, Harry; Kawai, T. 
NCI: Hwang, S.

Previous Awards Funded

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