U.S. Department of Health &
Human Services
OFFICE OF CLINICAL RESEARCH EDUCATION AND COLLABORATION OUTREACH
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Bench-to-Bedside and Back Program (BtB)
2012 Bench-to-Bedside and Back Program (BtB) Funded Projects
AIDS CATEGORY: Projects funded by Office of AIDS Research (OAR)
| Project | Institute or institution/Investigators |
|---|---|
| Anti-PD-1 antibody to eradicate HBV in HBV/HIV co-infection | NIAID: Barrett, Lisa; Kottilil, Shyam; Kohil, Anita;
Meissner, Eric CC: Suffredini, Anthony SAIC-Frederick: Osinusi, Anu Nationwide Children's Hospital: Walker, Christopher |
| Inflammation and Function of P-gp in HIV Infection of Brain | NIMH: Kreisl, William; Innis, Robert; Kapetanovic,
Suad NINDS: Nath, Avi CC: Morse, Caryn; Penzak, Scott University of California, San Diego: Best, Brookie; Heaton, Robert; Letendre, Scott |
| Targeting Lysyl Oxidase-like-2 to Inhibit Hepatic Fibrogenesis in HIV | CC: Morse, Caryn; Kovacs, Joseph; Wood, Brad NIAID: Meissner, Eric; Kottilil, Shyam NCI: Kleiner, David NIDDK: Heller, Theo; Gharib, Ahmed Inova Health System: Goodman, Zachary University of Maryland School of Medicine: Talwani, Rohit |
| Effect of HIV Superinfection on Disease Progression and Immune Response | NIAID: Quinn, Thomas; Porcella, Steve Johns Hopkins University: Gray, Ronald; Kirk, Gregory |
WOMEN'S HEALTH CATEGORY: Project funded by Office of Research on Women's Health (ORWH)
| Project | Institute or institution/Investigators |
|---|---|
| Molecular Epidemiology of Postpartum Involution of the Breast: Demonstration of Tools for Understanding Influences of Pregnancy on Breast Cancer Risk | NCI: Sherman, Mark; Fapuel-Badger, Jessica.; Hewitt,
Stephen; Balkam, JJ.; Gierach, Gretchen; Flanders, Kathy | CC: Bluemke, David Johns Hopkins University School of Medicine: Meeker, Alan University of Massachusetts Amherst: Arcaro, Kathleen |
GENERAL CATEGORY: Projects co-funded by Deputy Director for Intramural Research (DDIR) and ICs
| Project | Institute or institution/Investigators |
|---|---|
| CD22 Chimeric Antigen Receptors Targeting Acute Lymphoblastic Leukemia | NCI: Mackall, Crystal; Wayne, A.S.; Fry, Terry; Orentas,
Rimas; Haso, Waleed CC: Stroncek, David University of Pennsylvania: Levine, Bruce; June, Carl Children's Hospital of Philadelphia: Grupp, Stephan |
| Defining the Functional Role of STAT4 in human systemic lupus erythematosus | NIAMS: O'Shea, John NHGRI: Kastner, Dan; Remmers, Elaine NIDCR: Illei, Gabor Geza Cincinnati Children's Hospital: Harley, John |
RARE DISEASES CATEGORY: Projects co-funded by Office of Rare Diseases Research, National Center for Advancing Translational Sciences (ORDR/NCATS), the Deputy Director for Intramural Research (DDIR) and ICs
| Project | Institute or institution/Investigators |
|---|---|
| T cell adoptive therapy for viral infection after stem cell transplantation | NHLBI: Barrett, John NIAID: Douek, Daniel CC: Stroncek, David Baylor College of Medicine: Bollard, Catherine |
| Genetic Characterization and Outcome in Congenital Disorders of Muscle | NINDS: Bonneman, Carsten Children's Research Institute (CNMC): Walker, Christopher; Hoffman, Eric University of California, Davis: McDonald, Craig |
| Choroid Plexus-Directed Gene Therapy for Lysosomal Storage Disease | NICHD: Kaler, Stephen NHLBI: Kotin, Robert Children's Hospital of Philadelphia: Wolfe, John |
| Elucidation of cancer metabolism by Stable isotope-Resolved Metabolomics | NCI: Linehan, Marston NICHD: Roualt, Tracey Ann University of Lousiville: Lane, Andrew; Fan, Teresa |
| Treatment of Anti-NMDA receptor encephalitis | NINDS: Nath, Avi; Cortese, I.; Jacobson, S.; Roche,
K. CC: Hammoud, Dima Ali University of Pennsylvania: Dalmau, Joseph; Balice-Gordon, Rita |
| Metabolic phenotyping of Parkin mutation associated Parkinson's Disease | NHLBI: Sack, Michael NINDS: Youle, Richard University of Central Florida: Han, Xianlin |
| Metabolic Phenotyping in Methylmalonic Acidemia: Markers and Drug Response | NHGRI: Venditti, C.; Manoli, E. NIDDK: Chen, Kong Yin Children's National Medical Center: Tuchman, Mendel |
| Developing and validating membrane biomarkers in the muscular dystrophies | NICHD: Zimmerberg, Joshua; Blank, Paul; Basser, Peter;
Humphrey, Glen NINDS: Bonnemann, Carsten University of Massachusetts Worcester: Brown, Robert University of Maryland: Bloch, Robert |
INSTITUTE FUNDED: Projects funded by ICs
| Project | Institute or institution/Investigators |
|---|---|
| Blockade of Kisspeptin Signaling in Women | NICHD: Delaney, Angela Harvard Medical School: Seminara, Stephanie Massachusetts General Hospital: Crowley, William |
| Transcriptional responses to LAIV in bulk and single resident URT cells | NIAID: Subbarao, Kanta Stanford University: Sen, Adrish; Greenberg, Harry; He, X. |
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