OFFICE OF CLINICAL RESEARCH EDUCATION AND COLLABORATION OUTREACH
Bench-to-Bedside and Back Program (BtB)
2019 Bench-to-Bedside and Back Program (BtB) Funded Projects
Projects Funded by Bench-to-Bedside and Back Program (BtB) Program Funds
| Project | Institute or Institution Investigators | 
|---|---|
| Multiplex Imaging of Human and Mouse Tumors During Chemo-Immunotherapy | NCI: Germain, Ronald University of Pennsylvania: Vonderheide, Robert; Byrne, Katelyn  | 
              
| Signaling mechanisms in autosomal dominant polycystic kidney disease | NHLBI: Knepper, Mark; Chen, Lihe Yale University: Caplan, Michael; Somlo, Stefan  | 
              
| RAG deficiency: From pathophysiology to precise gene correction | NIAID: Notarangelo, Luigi; Malech, Harry; Belkaid,
                  Yasmine. NCI: Pittaluga, Stefania NHGRI: Segre, Julie Boston Children's Hospital: Pai, Sung-Yun Dana-Farber Cancer Institute: Genovese, Pietro CDC: Perelygina, Ludmila San Raffaele Foundation: Villa, Anna  | 
              
| Delivering Gene Therapies to Cure Sickle Cell Disease: Use of the Non-Human | NHLBI: Tisdale, John; Dunbar, Cynthia Magenta Therapeutics: Cooke, Michael Massachusetts General Hospital: Scadden, David  | 
              
| Colchicine for Treatment of Metabolic Syndrome | NICHD: Yanovski, Jack; Brady, Sheila; Chen, Kong CC: Yang, Shanna B NIDDK: Gubbi, Sriram; Walter, Peter Johns Hopkins University: Miller, Edgar; Demidowich, Andrew  | 
              
| Targeting Healing Pathways to Treat Diabetic Foot Ulcers | NIAMS: Morasso, Maria University of Miami: Tomic-Canic, Marjana  | 
              
| Cross-species circuit-based treatment development for anxiety | NIMH: Brotman, Melissa  University of Wisconsin: Kalin, Ned  | 
              
AIDS CATEGORY: Projects funded by Office of AIDS Research (OAR)
| Project | Institute or Institution Investigators | 
|---|---|
| Development of Second-Generation HIV-1 Maturation Inhibitors | NCI: Freed, Eric; Maldarelli, Frank CC: George, Jomy DFH Pharma, Inc: Wild, Carl  | 
              
RARE DISEASE CATEGORY: Projects Funded by Office of Rare Disease Research (ORDR) and supplemented by Bench-to Bedside Program Funds
| Project | Institute or Institution Investigators | 
|---|---|
| Metformin Trial for Oral Squamous Cell Cancer Prevention in Fanconi Anemia | NCI: Giri, Neelam; Kaplan, Rosandra; Alter, Blanche;
                  Szabo, Eva NICHD: Kamilaris, Crystal NIDCD: Van Waes, Carter NIDCR: Gardner, Pamela; Warner, Blake University of California, San Diego: Gutkind, Silvio  | 
              
| AAV2-GDNF Gene Therapy for Multiple System Atrophy | NINDS:  Goldstein, David; Ehrlich, Debra Ohio State University: Lonser, Russell; Bankiewicz, Krystof  | 
              
BEHAVIORAL & SOCIAL SCIENCES CATEGORY: Project funded by Office of Behavioral & Social Sciences Research (OBSSR)
| Project | Institute or Institution Investigators | 
|---|---|
| New non-opioid treatment for surgical pain | CC: Mannes, Andrew NCCIH: Bushnell, Catherine NCI: Schrump, David  | 
              
DIETARY SUPPLEMENTS CATEGORY: Project Funded by the Office of Dietary Supplements: (ODS)
| Project | Institute or Institution Investigators | 
|---|---|
| Effects of Treatment with a-Lipoic Acid and B3-Adrenergic Receptor Agonists | NIDDK: Abdul-Sater, Zahraa; Brown, Rebecca; Chen, Kong;
                  Cypess, Aaron Massachusetts General Hospital: Bredella, Miriam  | 
              
WOMEN'S HEALTH CATEGORY: Project funded by Office of Research on Women's Health (ORWH)
| Project | Institute or Institution Investigators | 
|---|---|
| Genomes and prenatal nutrition affecting preeclampsia and kidney outcomes | NIDDK: Kopp, Jeffrey NCI: Winkler, Cheryl Johns Hopkins University: Rosenberg, Avi Zwi; Hong, Xiumei; Wang, Xiaobin  | 
              


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