U.S. Department of Health &
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OFFICE OF CLINICAL RESEARCH EDUCATION AND COLLABORATION OUTREACH
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Bench-to-Bedside and Back Program (BtB)
2008 Bench-to-Bedside and Back Program (BtB) Funded Projects
GENERAL CATEGORY:
| Project | Institute or institution/Investigators |
|---|---|
| Targeting cancer-testis gene expression for lung cancer therapy | NCI: Schrump, David; Rao, Mashadev; Hong, Julie NIAID: Lobanenkov, Victor; Loukinov, Dmitri Ludwig Institute for Cancer Research: Old, Lloyd Weill Medical College at Cornell: Altorki, Nasser |
| Molecular mechanisms of glial cell modulation of chemotherapy-induced painful peripheral neuropathy | NINR: Wang, Xiao Min; Saligan, Leo CC: Mannes, Andrew University of Maryland: Dorsey, Susan; Renn, Cindy |
AIDS CATEGORY: Projects funded by Office of AIDS Research (OAR)
| Project | Institute or institution/Investigators |
|---|---|
| New strategies to decrease and eradicate HIV-1 reservoirs | NCI: Maldarelli, Frank; Freed, Eric; Palmer, Sarah;
Pathak, Vinay University of California, San Diego: Reid, Erin |
| HIV-1 suppression by Acyclovir in patients coinfected with human herpesviruses from basic mechanism to clinical application | NICHD: Margolis, Leonid; Biancotto, Angelique; Brichacek,
Beda; Grivel, Jean-Charles; Lisco, Andrea; Vanpouille, Christophe Case Western Reserve: Lederman, Michael; Rodriguez, Benigno |
| Non-invasive cardiac 3T MRI for evaluation of premature coronary artery disease and myocardial dysfunction in adolescents and young adults with HIV acquired in infancy and childhood | NIAID: Hadigan, Colleen NHLBI: Gharib, Ahmed NCI: Hazra, Rohan; Purdy, Julia Children's National Medical Center: Cross, Russell; Clauss, Sarah |
AIDS/MINORITY HEALTH CATEGORY:
| Project | Institute or institution/Investigators |
|---|---|
| Hepatitis B and HIV co-infection in Uganda | NIAID: Quinn, Thomas; Stabinski, Lara; Reynolds,
Steve Johns Hopkins University: Thio, Chloe; Kirk, Gregory; Gray, Ron; Thomas, David Uganda (Makere Medical School, Mulago Hospital): Ocama, Ponsiano; Serwadda, David |
| Development and evaluation of a nanoparticle-based HIV-1 p24 antigen assay for monitoring therapy in resource limited settings | NCI: Maldarelli, Frank FDA: Hewlett, Indira University of Washington: Frenkel, Lisa |
MINORITY HEALTH CATEGORY: Project funded by National Institute on Minority Health & Health Disparities
| Project | Institute or institution/Investigators |
|---|---|
| Toward molecular-marker based management of diabetic nephropathy in Pima Indians | NIDDK: Nelson, Robert; Weil, Jennifer; Knowler,
William University of Michigan: Kretzier, Matthias; Pennathur, Subrannian; Woolf, Peter |
RARE DISEASE CATEGORY: Projects Funded by Office of Rare Disease Research (ORDR)
| Project | Institute or institution/Investigators |
|---|---|
| Predicting the response to treatment using gene mutation profiling in metastatic melanoma patients | NHGRI: Samuels, Yardena University of South Carolina: Buckhaults, Phillip University of Texas-MD Anderson: Hwu, Patrick |
| Graft-Versus-Host Disease: novel cellular therapy using selective thawing of umbilical cord blood to obtain an aliquot for ex-vivo natural killer cell expansion and infusion following allogeneic hematopoietic stem cell transplantation | NHLBI: Childs, Richard; Lundqvist, Andreas; Berg,
Maria CC: Vasu, Sumithira |
| Evaluation of the platelet transcriptome expression profile in pulmonary arterial hypertension | CC: Machado, Roberto; Cuttica, Michael NHLBI: Raghavachari, Nalini; Gladwin, Mark Inova Fairfax Hospital: Nathan, Steven |
| Characterization of Jak/Stat activation in patients with monosomy 7 and the development of targeted therapy for patients using a Jak2 inhibitor | NHLBI: Sloland, Elaine; Young, Neal; Pfannes, Loretta;
Scheinberg, Phillip; Olnes, Matthew CC: Leitman, Susan Harvard University: Groopman, Jerome Temple University: Reddy, E. Premkumar Onconova Therapeutics, Inc.: Maniar, Manoj |
| Development of immunotherapeutic strategies to overcome tolerance in leukemia | NHLBI: Barrett, Austin John; Yong, Agnes; Le, Quan Imperial College of London: Rezvani, Katy; Apperley, Jane; Altmann, Danny |
| Recombinant human IL-& (CYT107) as immunomodulatory therapy for idiopathic CD4 lymphopenia: a phase I/IIA open-label pilot study | NIAID: Brenchley, Jason; Sereti, Irini; Hodge, Jessica;
Porter, Brian; Mannon, Peter NCI: Estes, Jake |
WOMEN'S HEALTH CATEGORY: Project funded by Office of Research on Women's Health (ORWH)
| Project | Institute or institution/Investigators |
|---|---|
| Immunogenicity of quadrivalent human papilloma virus vaccine (HPV Types 6, 11, 16, 18) in recipients of reduced intensity hematologic stem cell transplantation (HSCT) | Bedside: A. Shenoy, MD, NHLBI and P. Stratton, MD,
NICHD PBench: L. Pinto, MD and L. Wood, MD, NCI |
| Histaminergic pathways and energy intake in obese women | NICHD: Yanovski, Jack; Yanoff, Lisa; Cropp, Cheryl; Han,
Joan; Savastano, David NIDDK: Chen, Kong CC: Calis, Karim Sackler School of Medicine, Tel Aviv, Israel: Barak, Nir |
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