U.S. Department of Health &
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OFFICE OF CLINICAL RESEARCH EDUCATION AND COLLABORATION OUTREACH
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Bench-to-Bedside and Back Program (BtB)
2018 Bench-to-Bedside and Back Program (BtB) Funded Projects
Projects Funded by Bench-to-Bedside and Back Program (BtB) Program Funds
| Project | Institute or Institution Investigators |
|---|---|
| ProAgio for the treatment of pancreatic cancer | NCI: Alewine, Christine; Pastan, Ira; Figg, William Georgia State University: Liu, Zhi-Ren |
| Commensal microbiota as possible pathobiont in autoinflammatory disease | NEI: Caspi, Rachel; Raychaudhuri, Kumarkrishna;
Mattapallil, Mary Joseph; Bishop, Rachel; Okeagu, Chinwenwa NIAID: Strober, Warren; Fuss, Ivan; Goldbach-Mansky, Raphaela University of Pittsburgh: St. Leger, Anthony |
| Virus-specific T Cell Therapy for Treatment of Chronic Norovirus Infection | NIAID: Green, Lisbeth; Cohen, Jeff; Sosnovtsev,
Stanislav; Han, Alison Children's Research Institute: Bollard, Catherine; Hanley, Patrick; Hanajiri, Ryo |
| Novel CAR-T cells for the treatment of Chronic Lymphocytic Leukemia (CLL) | NCI: Kovalovsky, Damian; Gress, Ronald; Pittaluga,
Stefania The Scripps Research Institute-Florida: Rader, Christoph |
| Malignant transformation in patients with inherited RUNX1 mutations | NHGRI: Liu, Paul NCI: Hickstein, Dennis University of Chicago: Godley, Lucy FDA: Cunningham, Lea |
| Efficacy of the SHINGRIX zoster vaccine in Chronic Lymphocytic Leukemia | NHLBI: Wiestner, Adrian; Pleyer, Christopher; Sun, Clare;
Ahn, Inhye NIAID: Cohen, Jeff University of Washington: Koelle, David; Laing, Kerry |
| Investigation of DNMT3A and TET2 mutations in leukemia and clonal expansion | NHLBI: Zhao, Keji; Young, Neal; Hourigan,
Christopher NHGRI: Liu, Paul NCI: Batchelor, Eric |
| Rapid culture-free pathogen identification by genoproteomics | CC: Suffredini, Anthony; Dekker, John; Kovacs,
Joseph NIAID: Lionakis, Michail NIDDK: Koop, Jeffrey Walter Reed Army Institute of Research: McGann, Patrick T. |
Projects Funded by the Office of AIDS Research (OAR)
| Project | Institute or Institution Investigators |
|---|---|
| Translationally-competent yet defective HIV-1 proviruses and inflammation | NIAID: Imamichi, Hiromi; Lane, Clifford University of Minnesota: Baker, Jason; Grund, Birgit |
| Role of CNS co-infections in HIV Viral Reservoirs | NIAID: Sereti, Irini; Manion, Maura NCI: Maldarelli, Frank Frederick National Laboratory for Cancer Research: Deleage, Claire University of Minnesota: Boulware, David; Nicol, Melanie; Rhein, Joshua Makerere University: Meya, David |
Project funded by the Office of Dietary Supplements (ODS)
| Project | Institute or Institution Investigators |
|---|---|
| NAD supplementation in Werner Syndrome | NIA: Bohr, Vilhelm; Kariokkineth, Ajoy; Croteau,
Deborah Chiba University: Maezawa, Yoshiro |
Project funded by the Intramural Research Program (Director's Challenge Award)
| Project | Institute or Institution Investigators |
|---|---|
| Localization of Epileptogenic Foci using Diffusion Weighted MRI | CC: Butman, John NINDS: Zaghloul, Kareem; Inati, Sara NICHD: Basser, Peter The Henry M. Jackson Foundation: Pham, Dzung |
Project funded by the National Cancer Institute (NCI)
| Project | Institute or Institution Investigators |
|---|---|
| Intraprocedural cancer detection using enhanced ultrasound for intervention | CC: Wood, Bradford; Xu, Sheng NCI: Pinto, Peter; Choyke, Peter; Turkbey, Baris Rensselaer Polytechnic Institute: Yan, Pingkun |
Project funded by the National Institute on Minority Health and Health Disparities (NIMHD)
| Project | Institute or Institution Investigators |
|---|---|
| Tribal Turning Point: Metabolic Risk in American Indian Children | NIDDK: Sinha, Madhumita Joslin Diabetes Center: Kostic, Aleksandar |
Project funded by the Office of Behavioral and Social Sciences Research (OBSSR)
| Project | Institute or Institution Investigators |
|---|---|
| Maintenance treatment with novel biased mu agonists for opioid addiction | NIDA: Epstein, David The Scripps Research Institute-Florida: Bohn, Laura Research Triangle Institute: Blough, Bruce Virginia Commonwealth University: Negus, Sidney; Banks, Matthew |
Projects funded by the Office of Rare Diseases Research, National Center for Advancing Translational Sciences (ORDR/NCATS)
| Project | Institute or Institution Investigators |
|---|---|
| A novel therapy to improve antimicrobial function of neutrophils in CGD | NIAID: Zerbe, Crista University of North Dakota: Sharma, Jyotika |
| Human cell models and biomarkers of RYR1-related myopathies | NIDA: Harvey, Brandon NINR: Wires, Emily; Meilleur, Katherine NCATS: Henderson, Mark The Hospital for Sick Children: Dowling, James |
Project funded by the Office of Research on Women's Health (ORWH)
| Project | Institute or Institution Investigators |
|---|---|
| HDAC and IAP inhibition for ovarian and pancreatic cancers | NCI: Annunziata, Christina Johns Hopkins University: Azad, Nilofer |
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