U.S. Department of Health &
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OFFICE OF CLINICAL RESEARCH EDUCATION AND COLLABORATION OUTREACH
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Bench-to-Bedside and Back Program (BtB)
2004 Bench-to-Bedside and Back Program (BtB) Funded Projects
AIDS CATEGORY:
| Project | Institute or institution/Investigators |
|---|---|
| Neural substrates underlying motor control of a newly implanted hand transplant | NIAMS: Cendales; L NINDS: Cohen, Leonardo |
| Development of Non-invasive treatment for uterine leiomyoma (fibroids) | NIEHS: Davis, B. NCI: Partners NICHD: Stratton, Pam CC: Partners |
| Infrared and Near Infrared Image Guided Minimally Invasive Assessment of Renal Perfusion during Donor Nephrectomies and Partial Nephrectomies | NIDDK: Elster, E.; Kirk, Allan NCI: Partners ORS: Partners |
| Novel Approach for treatment of squamous cell malignancies with 17-AAG and bortezomib | NCI: Gius, D.; Neckers, Len NIDCD: Van Waes, Carter |
| Therapeutic application of intravascular nitrite for sickle cell disease | CC: Gladwin, M NHLBI: Cannon, Richard |
| Intermediate phenotype and genetic mechanisms for psychosis and cognitive disturbance in 22q11.2-hemideletion syndrome |
NCI: Meyer-Lindenberg, A. |
| Molecular profiling of response to proteasome inhibition by bortezomib (PS341) in a clinical trial of mantle cell lymphoma | NHLBI: Weistner, Adrian NCI: Wilson, Wyndham |
| A Phase I/II pilot study to evaluate the treatment of intraocular lymphoma with BL22 immunotoxin | NEI: Nussenblatt, Robert NCI: Pastan, Ira |
| Immunotherapy for Myelodysplastic Syndrome | NHLBI: Barrett, John NIAID: Douek, Daniel NCI: Rosenberg, Steve |
| A Phase I Treatment Trial of the Circadian Sleep Disturbance in Smith-Magenis Syndrome (SMS) | NHGRI: Smith, Ann CC: Grimes, George |
| Pre-clinical non-human primate studies of an invo selectable vector intended for use in a planned clinical trial of gene therapy for chronic granulomatous disease | NIAID: Malech, Harry NHLBI: Dunbar, Cynthia |
| solation and Characterization of Circulating Endothelial Cells in Primary Pulmonary Hypertension: Implications for Early Diagnosis and Novel Therapeutic Targets | CC: Solomon, Michael; Danner, Robert CIT: Partners |
| Evaluation of the anti-IL-2/IL-15Rb monoclonal antibody Hu MiK-b-1 in a therapeutic trial in patients with HAM/TSP and a test of hypotheses concerning the role of IL-15 in the maintenance of CD8+ memory T-cells and in the pathogenesis of HAM/TSP | NINDS: Jacobson, Steven NCI: Waldmann, Thomas CC: Fleisher, Thomas |
| Childhood Cancer and Plexiform Neurofibroma Tissue Microarray for Molecular Target Screening and Clinical Drug Development | NCI: Fox, E. NHGRI: Baird, K. |
| Molecular profiling and drug discovery for patients with PTEN Hamartomatous Tumor Syndromes (PHTS) | NCI: Dennis, P. NHGRI: Elkahoun, A. |
| Assessing the safety and immunogenicity of a therapeutic vaccination strategy using a DNA plasmid vaccine prime and a recombinant adenovector boost in HIV infected adults | NIAID: Graham, Barney NCI: Partners |
| Targeting vascular endothelial growth factor-A (VEGF-A) and receptor-2 (VEGFR-2) for the treatment of Primary Effusion Lymphoma | NCI: Tosato, Giovanna; Yarchoan, Robert NIAID: Partners |
| Pediatric NeuroAIDS in the HAART Era: Identification of Disease Markers and Therapeutic Targets | NCI: Hazra, R. NINDS: Major, Eugene; Schwartz, L. |
| Treatment of Primary-Effusion Lymphoma with Combination Virolytic and Cytotoxic Chemotherapy | NCI: Yarchoan, Robert; Little, Richard NIAID: Cohen, Jeffrey |
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