U.S. Department of Health &
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OFFICE OF CLINICAL RESEARCH EDUCATION AND COLLABORATION OUTREACH
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Bench-to-Bedside and Back Program (BtB)
2016 Bench-to-Bedside and Back Program (BtB) Funded Projects
Projects Funded by Bench-to-Bedside Program Funds
| Project | Institute or Institution/Investigators |
|---|---|
| Intervention to Correct Mitochondrial Function in Cockayne Syndrome | NIA: Bohr, Vilhelm; Karikkineth, Ajoy; Egan, Josephine
Mary; Croteau, Deborah NCI: Kraemer, Kenneth; DiGiovanna, John NEI: Brooks, Brian University of Florida: Kang, Peter |
| The Role of Mutant STAT3 in Airway Epithelium Mucus and Host Defense* | NHLBI: Olivier, Kenneth NIAID: Freeman, Alexandra University of North Carolina at Chapel Hill: Boucher, Richard; Chen, Gang |
| Investigations of Juvenile Neuronal Ceroid Lipofuscinosis (CLN3)* | NICHD: Porter, Forbes Washington University: Ory, Daniel; Jiang, Xuntian Albert Einstein College of Medicine: Walkley, Steven |
| Microbiome and Uveitis* | NEI: Sen, Hatice; Caspi, Rachel; Chaigne-Delalande,
Benjamin UCLA: Braun, Jonathan |
| Defining Skin Immunity at the Bite Site of Key Insect Vectors in Humans | NIAID: Valenzuela, Jesus; Memoli, Matthew; Ribiero, Jose; Kamhawi, Shaden; Oliveira, Luiz Fabiano |
| Cellular Basis of Differential Hormone Response In Peripartum Mood Disorder | NIMH: Schmidt, Peter; Berman,
Karen NIAAA: Goldman, David UNC Chapel Hill: Meltzer-Brody, Samantha; Rubinow, David; Schiller, Crystal Erasmus University Medical Center: Bergink, Veerle |
| AMPAR Mechanism of Ketamine Antidepressant Action: Translational Validation | NIMH: Zarate, Carlos NIA: Moaddel, Ruin University of MD Baltimore: Gould, Todd; Zanos, Panos |
| Peptidomic Diagnosis and Monitoring of Mycobacterial Infection in HIV/AIDS | CC: Zelazny, Adrian; Zhen, Zhao NIAID: Holland, Steven; Sereti, Irini NHLBI: Olivier, Kenneth Arizona State University: Hu, Tony Ye |
| A Study of Combination HIV-Specific Antibodies in Infected Individuals* | NIAID: Chun, Tae-Wook; Sneller, Michael; Moir,
Susan Rockefeller University: Caskey, Marina; Nussenzweig, Michel |
| Effects of Sucralose on Gut Transporters and Microbiota in Minority Women | NIDDK: Rother, Kristina; Meni, Allison Institute for Genome Sciences: Fraser-Ligett, Claire Purdue University: Swithers, Susan |
| Therapeutic Targets in African Americans with Primary Aldosteronism* | NICHD: Stratakis, Constantine University of Michigan: Rainey, William; Tomlins, Scott |
| Prostate Cancer Screening Enabled by Low-cost Ultrasound | CC: Wood, Bradford; Seifabadi, Reza; Dahut, William NCI: Turkbey, Baris Ismail; Merino, Maria; Pinto, Peter Johns Hopkins: Boctor, Emad; Rahmim, Arman; Aalamifar, Fereshteh |
* Indicates 1-year projects
RARE DISEASE CATEGORY: Projects Funded by Office of Rare Disease Research (ORDR) and supplemented by Bench-to-Bedside Program Funds
| Project | Institute or Institution/Investigators |
|---|---|
| Deciphering Immune Dysregulation Due to Germline Ctla4 Mutations | NIAID: Uzel, Gulbu Yale University: Meffre, Eric |
| Melanocortin agonist to bypass leptin resistance of Bardet-Biedl Syndrome | NICHD: Yanovski, Jack; Brady, Sheila; Broadney,
Miranda CC: Courville, Amber NIDDK: Chen, Kong University of Tennessee: O'Connell, Kristen; Han, Joan; McAllan, Liam; Smith, Webb |
BEHAVIORAL & SOCIAL SCIENCES CATEGORY: Project funded by Office of Behavioral & Social Sciences Research (OBSSR)
| Project | Institute or Institution/Investigators |
|---|---|
| A Novel Mechanism-Based Treatment for Pediatric Anxiety Disorders | NIMH: Pine, Daniel Washington University SOM: Sylvester, Chad |
| Nicotinic Receptor Genetic Variation and Alcohol Reward | NIAAA: Ramchandani, Vijay; Goldman, David; Momenan, Reza;
Hodgkinson, Colin NIDA: Stein, Elliot University of Pennsylvania: Di Biasi, Mariella; Dani, John |
DIETARY SUPPLEMENTS: Project Funded by the Office of Dietary Supplements (ODS)
| Project | Institute or Institution/Investigators |
|---|---|
| Nicotinamide Riboside Effects on Skeletal Muscle Function in Heart Failure | NHLBI: Sack, Michael NHLBI: Hwang, Paul University of Washington: Tian, Rong; O'Brien, Kevin Walter Reed Navy Medical Center: Flanagan, Michael |
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