Bench-to-Bedside and Back Program (BtB)
Past Five Years Awards
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| Funded by | Year | Project | Institute or Institution/Investigators |
|---|---|---|---|
| Office of Behavioral & Social Sciences Research (OBSSR) | 2025 | Investigating the role of effort before a meal on food intake and obesogenic food behaviors | CC: Farmer, Nicole |
| Office of Research on Women's Health (ORWH) | 2025 | Ultrasound for Dynamic TMJ Imaging: MRI-Guided Structure Labeling and AI-Assisted Image Acquisition | NIDCR: Lee, Janice; Almpani, Konstantinia; Venkateswaran, Vidhya |
| Office of Dietary Supplements (ODS) | 2025 | Effect of dietary dihomo-gamma-linolenic acid on inflammation-related conditions | NHLBI: Remaley, Alan; Amar, Marcelo; Yang, Zhihong |
| Office of Dietary Supplements (ODS) | 2025 | Antioxidant Therapy for Smith-Lemli-Opitz Syndrome | NICHD: Porter, Forbes; Rahhal, Samar D.; Labor, Desiree |
| Office of Dietary Supplements (ODS) | 2025 | Combining nicotinamide riboside with ketogenic diet to prevent fatty liver disease | NIDDK: Hengist, Aaron; Chung, Stephanie Therese |
| Office of AIDS Research (OAR) | 2025 | Development of Novel HIV DNA-nanoparticle Vaccine for Clinical Application | NCI: Felber, Barbara; Maldarelli, Frank |
| Office of AIDS Research (OAR) | 2025 | Treatment of HIV Infection using an anti-HIV antibody-like molecule eCD4-Ig | NIAID: Chun, Tae-Wook; Susan Moir |
| Office of Clinical Research Education and Collaboration Outreach (OCRECO) Bench-to-Bedside Program (BtB) | 2025 | Developing Red Cell-specific Spleen Tyrosine Kinase (SYK) Inhibitors for Treating Sickle Cell Disease | NHLBI: Thein, Swee Lay |
| Office of Clinical Research Education and Collaboration Outreach (OCRECO) Bench-to-Bedside Program (BtB) | 2025 | Nanobody-based CAR targeting of an endogenous retroviral envelope for the treatment of glioblastoma | NCI: Taylor, Naomi; Altan-Bonnet, Gregoire Yves |
| Office of Clinical Research Education and Collaboration Outreach (OCRECO) Bench-to-Bedside Program (BtB) | 2025 | The role of sandfly bites on regulating skin oxygenation and immune cell function in mice and humans: implications for leishmaniasis severity | NIAID: Oliveria, Luiz; Marques, Adriana |
| Office of Clinical Research Education and Collaboration Outreach (OCRECO) Bench-to-Bedside Program (BtB) | 2025 | New biologics to treat asthma in inner city populations sensitized to rodents | NEIHS: Mueller, Geoffrey |
| Office of Clinical Research Education and Collaboration Outreach (OCRECO) Bench-to-Bedside Program (BtB) | 2025 | Translating Activity of Bitopertin in Diamond Blackfan anemia syndrome to show therapeutic potential in Myelodysplastic Syndrome patients | NCI: McGraw, Kathy; Taylor, Naomi |
| Office of Clinical Research Education and Collaboration Outreach (OCRECO) Bench-to-Bedside Program (BtB) | 2025 | Translational Approaches Unraveling Birdshot Chorioretinopathy Disease Etiology and Advancing Therapeutic Innovations | NEI: Mattapallil, Mary; Caspi, Rachel |
| Office of Clinical Research Education and Collaboration Outreach (OCRECO) Bench-to-Bedside Program (BtB) | 2025 | Using Artificial Intelligence and Radiomics to Predict Hepatocellular Carcinoma Risk in Cirrhosis Patients | NIDDK: Hsu, Christine; Liang, Jake |
| Office of Clinical Research Education and Collaboration Outreach (OCRECO) Bench-to-Bedside Program (BtB) | 2025 | Does vaginal microbiome seeding of cesarean section delivered infants reduce the risk of obesity and atopic disease? | NIAID: Hourigan, Suchitra; Guerrerio, Pamela |
| Office of Clinical Research Education and Collaboration Outreach (OCRECO) Bench-to-Bedside Program (BtB) | 2025 | Developing a Theranostic Agent for Multiple Myeloma Based on a BCMA-targeted Nanobody | NCI: Choyke, Peter; Hill, Elizabeth; Young, Ryan |
| Office of Clinical Research Education and Collaboration Outreach (OCRECO) Bench-to-Bedside Program (BtB) | 2025 | Translating Genetic Discoveries into Prognostic Relevance for Waldenström Macroglobulinemia | NCI: Berndt, Sonja I.; Jianxin, Shi |
| Office of Clinical Research Education and Collaboration Outreach (OCRECO) Bench-to-Bedside Program (BtB) | 2025 | Peptide eye drops to delay and stabilize retinal degeneration progression | NEI: Becerra, Patricia; Brooks, Brian |
| Co-funded by Office of Research on Women's Health (ORWH) & Office of Clinical Research Education and Collaboration Outreach (OCRECO) | 2024 | Deep immunophenotyping of breast milk and maternal immunity over lactation | NIAID: Manthiram, Kalpana; Corral, Dan; Hourigan, Suchitra; Schwartzberg, Pamela; Xu, Qin |
| Co-funded by Office of Research on Women's Health (ORWH) & Office of Clinical Research Education and Collaboration Outreach (OCRECO) | 2024 | Role of Eosinophils in Spontaneous Coronary Artery Disease Pathogenesis | NIAID: Klion, Amy; Khoury, Paneez; Fay, Michael |
| Co-funded by Office of Research on Women's Health (ORWH) & Office of Clinical Research Education and Collaboration Outreach (OCRECO) | 2024 | A pilot study for treating chronic fatigue syndrome (ME/CFS) | NHLBI: Hwang, Paul; Wang, Ping-yuan |
| Office of Dietary Supplements (ODS) | 2024 | Role of Blautia wexlerae in GLP1 Secretion after Dietary Fatty Acids | NICHD: Yanovski, Jack; Brady, Sheila |
| Office of AIDS Research (OAR) | 2024 | Biomarkers and biology of aging in people with HIV | NIAID: Sereti, Irini; Brenchley, Jason; Epling, Brian |
| Office of AIDS Research (OAR) | 2024 | Early metabolic effects of Dolutegravir or Tenofovir Alafenamide | CC: Kuruppu, Janaki; Kovacs, Joseph |
| Office of AIDS Research (OAR) | 2024 | Non-canonical integrase strand transfer inhibitor resistance pathways | NCI: Freed, Eric |
| Office of AIDS Research (OAR) | 2024 | Intensification of antiviral therapy with lenacapavir in people with HIV | NIAID: Chun, Tae-Wook; Sneller, Michael; Moir, Susan |
| Office of Clinical Research Education and Collaboration Outreach (OCRECO) Bench-to-Bedside Program (BtB) | 2024 | Development of a novel multi-agent targeted therapy for multiple myeloma | NCI: Young, Ryan; Young, Elizabeth |
| Office of Clinical Research Education and Collaboration Outreach (OCRECO) Bench-to-Bedside Program (BtB) | 2024 | Metformin eye drops: topical delivery as a potential treatment of AMD | NEI: Sharma, Ruchi; Bharti, Kapil; Chew, Emily; Keenan, Tiarnan; Farnoodian Tedrick, Mitra |
| Office of Clinical Research Education and Collaboration Outreach (OCRECO) Bench-to-Bedside Program (BtB) | 2024 | Acamprosate in C9orf72-related ALS and FTD (ACALS) | NIA: Traynor, Bryan |
| Office of Clinical Research Education and Collaboration Outreach (OCRECO) Bench-to-Bedside Program (BtB) | 2024 | Environment, genes, and sex modulate neuro-reproductive activity | NIEHS: Shaw, Natalie; Archer, Trevor |
| Office of Clinical Research Education and Collaboration Outreach (OCRECO) Bench-to-Bedside Program (BtB) | 2024 | Mechanistic Insights to New Drugs for Treating Sickle Cell Disease | NHLBI: Mizuno, Naoko; Biertuempfel, Christian; Thein, Swee-Lay |
| Office of Clinical Research Education and Collaboration Outreach (OCRECO) Bench-to-Bedside Program (BtB) | 2024 | Defining Mechanisms Linking Ultra-Processed Foods to Inflammation | CC: Maki, Katherine |
| Office of Clinical Research Education and Collaboration Outreach (OCRECO) Bench-to-Bedside Program (BtB) | 2024 | Contribution of Inflammation to the Pathogenesis of RUNX1-FPDMM | NHGRI: Liu, Paul |
| Office of Clinical Research Education and Collaboration Outreach (OCRECO) Bench-to-Bedside Program (BtB) | 2024 | Immunoproteomic Profiling of Venovenous Extracorporeal Membrane Oxygenation | NHLBI: Kanth, Shreya; Torabi-Parizi, Parizad |
| Office of Clinical Research Education and Collaboration Outreach (OCRECO) Bench-to-Bedside Program (BtB) | 2024 | Soluble Adenylyl Cyclase Inhibition in Pulmonary Arterial Hypertension | NHLBI: Hersi, Kadija; Elinoff, Jason |
| Office of Research on Women's Health (ORWH) | 2023 | Novel Gut Microbiome Factors in Pregnancy & Early Childhood: ETCHED Study | NIDDK: Sinha, Madhumita |
| Office of Dietary Supplements (ODS) | 2023 | Effect of dietary fish oil enriched in very-long-chain PUFAs | NHLBI: Remaley, Alan; Danner, Robert; Yang, Zhihong; Amar, Marcelo |
| National Institute on Minority Health & Health Disparities (NIMHD) | 2023 | Linkage between social determinants of health and cardiometabolic disease | NIDDK: Nieman, Lynnette; Gharib, Ahmed; Sumner, Anne |
| Office of AIDS Research (OAR) | 2023 | Mechanisms of HIV Persistence in Perinatally Infected Children | NCI: Maldarelli, Frank; Kearney, Mary |
| Office of AIDS Research (OAR) | 2023 | A JCV-specific T cell bank for progressive multifocal leukoencephalopathy | NINDS: Cortese, Irene |
| Office of Clinical Research Education and Collaboration Outreach (OCRECO) Bench-to-Bedside Program (BtB) | 2023 | AI and patient-derived models to identify personalized therapy for gliomas | NCI: Wu, Jing |
| Office of Clinical Research Education and Collaboration Outreach (OCRECO) Bench-to-Bedside Program (BtB) | 2023 | Development of in vivo gene therapy for sickle cell disease | NHLBI: Tisdale, John; Uchida, Naoya; Liu, Xiong |
| Office of Clinical Research Education and Collaboration Outreach (OCRECO) Bench-to-Bedside Program (BtB) | 2023 | Quantitative Autoantibody Levels and Proteomic Endotypes in Myositis-ILD | NHLBI: Suffredini, Anthony F |
| Office of Clinical Research Education and Collaboration Outreach (OCRECO) Bench-to-Bedside Program (BtB) | 2023 | Elucidating innate immune dysregulation in Sickle Cell Disease | NHLBI: Shet, Arun; Swenson, Rolf; Goplan, Parachalil |
| Office of Clinical Research Education and Collaboration Outreach (OCRECO) Bench-to-Bedside Program (BtB) | 2023 | Defining the Immunophenotype of Down Syndrome Regression Disorder | NIMH: Mooneyham, GenaLynne; Bartley, Chris |
| Office of Clinical Research Education and Collaboration Outreach (OCRECO) Bench-to-Bedside Program (BtB) | 2023 | Investigation into Opioid Signaling of Ketamine in Anxiety and Depression | NIDA: Michaelides, Michael |
| Office of Clinical Research Education and Collaboration Outreach (OCRECO) Bench-to-Bedside Program (BtB) | 2023 | The immunologic impact of optimized post-transplant cyclophosphamide dosing | NCI: Kanakry, Christopher; Figg, Douglas |
| Office of Clinical Research Education and Collaboration Outreach (OCRECO) Bench-to-Bedside Program (BtB) | 2023 | Endothelial Senescence in Acute and Late COVID-19 Vasculopathy | CC: Danner, Robert; Keshavarz, Ali; Suffredini, Anthony; Chertow, Daniel |
| Office of Clinical Research Education and Collaboration Outreach (OCRECO) Bench-to-Bedside Program (BtB) | 2023 | JAK/STAT inhibitors for treatment of systemic Köhlmeier-Degos Disease | NHLBI: Cudrici, Cornelia; Boehm, Manfred; Rosing, Douglas; Leifer, Eric |
| Office of Clinical Research Education and Collaboration Outreach (OCRECO) Bench-to-Bedside Program (BtB) | 2023 | Eosinophilic esophagitis (EoE) screening in resource-limited populations | NIAID: Constantine, Gregory; Khoury, Paneez; Klion, Amy |
| Office of Research on Women's Health (ORWH) | 2022 | Diversification of the pregnant vaginal microbiome-implications for health | NIAID: Hourigan, Suchitra |
| Office of Behavioral & Social Sciences Research (OBSSR) | 2022 | Kinetics and target engagement for a Phase II trial of RTX for cancer pain | CC: Mannes, Andrew; Sapio, Matthew; Pritchard, William; Karanian, John; Iadarola, Michael; Wood, Bradford |
| Office of Behavioral & Social Sciences Research (OBSSR) | 2022 | Vitamin C dysregulation in obese women with and without HIV | NIDDK: Ebenuwa, Ifechukwude; Levine, Mark; Chen, Kong; Gharib, Ahmed; Wilkins, Kenneth; Violet, Pierre-Christian |
| Office of AIDS Research (OAR) | 2022 | Anti-HIV antibodies to eliminate HIV reservoirs | NIAID: Chun, Tae-Wook |
| Office of Clinical Research Bench-to-Bedside Program (BtB) | 2022 | Transmission of Aerosols from the Upper Airway into the Lungs by Snoring | NHLBI: Fennelly, Kevin; Olivier, Kenneth; Kim, Dong-Yun |
| Office of Clinical Research Bench-to-Bedside Program (BtB) | 2022 | Model of sequential dengue in exposed humans using a monovalent vaccine | NIAID: Katzelnick, Leah; Odio, Camila; Whitehead, Steve; Manning, Jessica |
| Office of Clinical Research Bench-to-Bedside Program (BtB) | 2022 | Non-infectious lung disease after allogeneic stem cell transplantation | CC: Suffredini, Anthony; Herscovitch, Peter |
| Office of Clinical Research Bench-to-Bedside Program (BtB) | 2022 | Clonal hematopoiesis of indeterminate potential in HIV inflammation | NIAID: Sereti, Irini; Rocco, Joseph |
| Office of Clinical Research Bench-to-Bedside Program (BtB) | 2022 | Exploiting inhibitory role of CD3zeta ITAMs to improve tumor immunotherapy | NICHD: Love, Paul |
| Office of Clinical Research Bench-to-Bedside Program (BtB) | 2022 | The role of splicing factor mutations in Chronic Myelomonocytic Leukemia | NCI: Larson, Daniel; Palangat, Murali |
| Office of Clinical Research Bench-to-Bedside Program (BtB) | 2022 | Targeted Lipid Nanoparticles for Gene Editing of Blood Stem Cells In Vivo | NHLBI: Larochelle, Andre; Smith, Richard; Rao, Anirudh; Hong, Sogun |
| Office of Clinical Research Bench-to-Bedside Program (BtB) | 2022 | Time Restricted Eating, Ketone Metabolism and CD4+ T Cell Immunomodulation | NIDDK: Chung, Stephanie; Chen,Kong; Courville, Amber |
| Office of Clinical Research Bench-to-Bedside Program (BtB) | 2022 | Natural History Changes in Congenital Muscular Dystrophy MRI Biomarkers | NINDS: Bonnemann, Carsten; Foley, Reghan |
| Cancer Moonshot Funds - National Cancer Institute (NCI) Administrative Supplements | 2021 | TME informed NK cell therapy for pediatric sarcomas | NCI: Kaplan, Rosandra; Wedekind, Mary Frances; Glod, John; Choyke, Peter; Widemann Brigitte |
| Cancer Moonshot Funds - National Cancer Institute (NCI) Administrative Supplements | 2021 | Targeting neuroendocrine tumors with DLK1 directed immunotherapy | NCI: Nitin, Roper; Widemann, Brigitte; Del Rivero, Jaydira |
| Cancer Moonshot Funds - National Cancer Institute (NCI) Administrative Supplements | 2021 | Determinants of pre-mature CAR T cell senescence in B cell cancers | NIA: Weng, Nan-ping |
| Cancer Moonshot Funds - National Cancer Institute (NCI) Administrative Supplements | 2021 | B2B and Back: CD22 and CD19/22 CAR immunotherapies for childhood leukemia | NCI: Taylor, Naomi; Altan-Bonnet, Gregoire Yves; Shah, Nirali |
| Cancer Moonshot Funds - National Cancer Institute (NCI) Administrative Supplements | 2021 | Alternative splicing of CD22 following Inotuzumab | NCI: Shah, Nirali |
| Office of Research on Women's Health (ORWH) | 2021 | A novel osteoporosis treatment targeting the osteoclast surface La protein | NICHD: Chernomordik, Leonid |
| National Institute on Minority Health & Health Disparities (NIMHD) | 2021 | Sleep-time blood pressure and risk of chronic kidney disease progression | NIMHD: El-Toukhy, Sherine |
| Office of Dietary Supplements (ODS) | 2021 | Effect of Nicotinamide Riboside on Ketosis, Fat Oxidation & Metabolic Rate | NIDDK: Hall, Kevin; Rotman, Yaron; Gharib, Ahmed; Courville, Amber; Chen, Kong |
| Office of Clinical Research Bench-to-Bedside Program (BtB) | 2021 | RBC health as a novel biomarker of a successful outcome in HSCT for SCD | NHLBI: Fitzhugh, Courtney |
| Office of Clinical Research Bench-to-Bedside Program (BtB) | 2021 | Targeting ER proteostasis to monitor and treat ischemic stroke | NIDA: Harvey, Brandon; Trrychta, Kathleen |
| Office of Clinical Research Bench-to-Bedside Program (BtB) | 2021 | Smart Lung Biopsy with Impedance and Artificial Intelligence | CC: Wood, Bradford; Xu, Sheng; Karanian, John; Pritchard, William |
| Office of Clinical Research Bench-to-Bedside Program (BtB) | 2021 | Identification of therapies that block PD-L1 enriched exosome biogenesis | NCATS: Thomas, Craig |
| Office of Clinical Research Bench-to-Bedside Program (BtB) | 2021 | Mitochondria-ER contacts in the pathogenesis and therapy of NAFLD | NIEHS: Santos, Janine |
| Office of Clinical Research Bench-to-Bedside Program (BtB) | 2021 | Network-based mechanisms of Mindfulness Training for Youth Nicotine Vaping | NIDA: Salmeron, Betty Jo; Yang, Yihong; Curtis, Brenda Lynette; Ross, Thomas |
| Office of Clinical Research Bench-to-Bedside Program (BtB) | 2021 | Role of Metal Ion Transporter ZIP8 in Alcohol Related Behaviors | NIAAA: Ramchandani, Vijay; Momenan, Reza; Venkatesh, Shyamala; Diazgranados, Nancy |
| Office of Clinical Research Bench-to-Bedside Program (BtB) | 2021 | Plasma EBV DNA based diagnosis of endemic Burkitt Lymphoma in Africa | NCI: Mbulaiteye, Sam; Sampson, Joshua |
| Office of Clinical Research Bench-to-Bedside Program (BtB) | 2021 | A targeted treatment for the monogenic autoimmune syndrome APECED | NIAID: Lionakis, Michail; Germain, Ronald |
| Office of Clinical Research Bench-to-Bedside Program (BtB) | 2021 | Endocannabinoid/CB1R system in long-term pulmonary complications of COVID | NIAAA: Resat, Cinar |
| Office of Clinical Research Bench-to-Bedside Program (BtB) | 2021 | Molecular Imaging of Multiple Myeloma Targeting BCMA | NCI: Choyke, Peter; Mena, Esther; Young, Ryan |