U.S. Department of Health &
Human Services
OFFICE OF CLINICAL RESEARCH EDUCATION AND COLLABORATION OUTREACH
Overview
Programs
Resources
Staff
Bench-to-Bedside and Back Program (BtB)
2007 Bench-to-Bedside and Back Program (BtB) Funded Projects
GENERAL CATEGORY:
| Project | Institute or institution/Investigators |
|---|---|
| Dynamic Measurement and modeling of Immune Homeostasis and Reconstitution in Pre-clinical and Clinical Studies of Cytokine Therapy and Allogeneic Hematopoietic Stem Cell Transplantation (AHSCT) | NCI: Gress, Ron; Chu, Yu-Waye; Hakim, Fram;
Telford, William; Sidorov, Igor; Dimitrov, Dimiter Hackensack University Medical Center: Korngold, Robert |
AIDS CATEGORY:
| Project | Institute or institution/Investigators |
|---|---|
| Intensification of Antiretroviral Therapy Using HIV Integrase Inhibitor (MK-0518) to Assess Decay of Viral Reservoirs in Peripheral Blood and Gut-Associated Lymphoid Tissue of Chronically Infected Patients | NIAID: Chun, Tae-Wook ; Moir, Susan;
Kottilil, Shyam CC: Healy, Letha; Penzak, Scott R. University of Toronto: Kovacs, Colin; Loufty, Mona George Washington University: Ward, Douglas |
| Humoral Response Profiling of Viral and Cellular Tumor Antigens for Predicting, Diagnosing, and Monitoring HIV Malignancies | NIDCR: Burbelo, Peter; Iadorola, Michael CC: Kovacs, Joseph; Healy, Letha |
| 1H Magnetic Resonance Spectroscopy for Quantification of Hepatic Triglyceride Content: Validation and Application in HIV-infected Patients | NIAID: Berger, Ed University of Washington: Casper, Corey |
| Development of Immunotoxins against Kaposi's Sarcoma Associated Herpesvirus for Treatment of Multicentric Castleman�s Disease (MCD) | NIAID: Berger, Ed University of Washington: Casper, Corey |
RARE DISEASES CATEGORY:
| Project | Institute or institution/Investigators |
|---|---|
| Antiproliferative Therapy for Severe Pulmonary Arterial Hypertension | NHLBI: Boehm, Manfred; Machado, Roberto;
Gladwin, Mark CC: Cuttica, Michael J.; Cochard, Audrey; Barnett, Christopher Inova Fairfax Hospital: Nathan, Steven |
| Characterization of Glycosphingolipid Accumulation in Smith-Lemli-Opitz Syndrome and Treatment with N-butyldsoxynojirimycin | NICHD: Porter, Forbes University of Oxford (UK): Platt, Fran |
| Life-Threatening Pulmonary Complications of Organ Transplantation: An Investigation of the Pathogenesis of Bronchiolitis Obliterans and Its Novel Treatment with Aerosolized Liposomal Cyclosporine A | NHLBI: Childs, Richard CC: Suffredeini, Anthony; Danner, Robert University of Maryland: Iacono, Aldo; Griffith, Bartley; Terrin, Michael |
| Role of Pathogen-specific IgE and histamine release in the hyper-IgE syndrome | NIAID: Freeman, Alexandra; Holland, Steve; Welch, Pam;
DeCastro, Rosamma; Anderson, Victoria NCI: Turner, Maria NHGRI: Davis, Joie CC: Darnell, Dirk Uniformed Services University of Health Sciences: Mitre, Edward; Torrero, Marina; Hubner, Marc; Larson, David University of California, San Francisco: Puck, Jennifer |
| WAGR Syndrome: Clinical Characterization and Correlation with Geneotype | NICHD: Han, Joan; Lu, Bai; Rennert, Owen; Yanovski,
Jack NEI: Brooks, Brian NIDCR: Domingo, Demetrio NIMH: Swedo, Susan NIDDK: Kopp, Jeffrey Georgetown University Medical Center: Lacbawan, Felicitas Uniformed Services University of Health Sciences: Sharp, Stephen Johns Hopkins University: Bengel, Frank M. |
| Sensitivity and resistance to Rituximab therapy in SLL/CLL: the role of antigenic modulation, immune effector mechanisms and direct pro-apoptotic signaling | NHLBI: Weistner, Adrian NCI: Wilson, Wyndham University of Virginia: Weiss, Geoffrey; Taylor, Ron |
| Quantification of urinary oxidized lipids, 8-hydroxyguanine, and 8-hydroxy-2'-deoxyguanosine in Friedreich ataxia patients undergoing idebenone treatment in a phase II double-blind placebo-controlled study | NINDS: Fischbeck, Kenneth; DiProspero, Nicholas University of Pennsylvania: Blair, Ian; Wilson, Robert |
| Translational Studies of Hereditary Spastic Paraplegias types SPG4 and SPG20 | NINDS: Blackstone, Craig; Bakawska, Joanna NIDDK: Hurley, James; Yang, Dong |
| Genetics of inherited paragangliomas and gastric stromal tumors associated with adrenal and other tumors | NICHD: Stratakis, Constantine Cleveland Clinic Genomics Medicine Institute: Eng, Charis |
MINORITY HEALTH & HEALTH DISPARITIES CATEGORY
| Project | Institute or institution/Investigators |
|---|---|
| Effects of Beta Cell Rest in Young Individuals with Type 2 Diabetes and in Relevant Animal Model | NIDDK: Rother, Kristina; Brown, Rebecca UCLA: Butler, Peter |
| Identification of Predictive Biomarkers of Asthma Exacerbations in Exhaled Breath Condensates from High Risk Patients | NHLBI: Levine, Stewart; Kaler, Maryann Johns Hopkins University: Jackman, Joany; Rothman, Richard |
| Ethnic Differences in Triglyceride Levels and Vascular Disease: A Study of Premenopausal African American and Caucasian Women | NIDDK: Sumner, Anne; Ricks, Madia NHLBI: Sachdev, Vandana CC: Denkinger, Blakeley Harvard School of Public Health: Sacks, Frank Brigham & Women's Hospital: Aikawa, Masanori |
| Contribution of Stromal Free Hemoglobin, Red Cell Membranes, and Red Cell Lysate on Nitric Oxide Inactivation in the Chronic Hemolytic State | NHLBI: Gladwin, Mark; Machado, Roberto CC: Solomon, Steven; Klein, Harvey; Natanson, Charles |
WOMEN'S HEALTH CATEGORY
| Project | Institute or institution/Investigators |
|---|---|
| Targeting HPV E2 as a vaccine against HPV mediated CIN1 and CIN2 | NCI: Khleif, Samir; Berzofsky, Jay; Qian,
Jiahua Gynecologic Oncology Group: Vaccine Working Group, Vaccine Subcommitte, GOG University of Miami: Lucci, Joseph University of Oklahoma: Walker, Joan |
Social Media Links