U.S. Department of Health & Human
Services
OFFICE OF CLINICAL RESEARCH EDUCATION AND COLLABORATION OUTREACH
Bench-to-Bedside and Back Program (BtB)
Current Awards
2025 Bench-to-Bedside and Back Program (BtB) Funded Projects
Office of Clinical Research Education and Collaboration Outreach (OCRECO): Projects Funded by Bench-to Bedside Program Funds
| Project | Institute or Institution/Investigators |
|---|---|
| Peptide eye drops to delay and stabilize retinal degeneration progression |
NEI: Becerra, Patricia; Brooks, Brian NCATS: Ottinger, Elizabeth; Xu, Xin; Jin, Haksong University of Louisville Research Foundation, Inc: McCall, Maureen |
| Translating Genetic Discoveries into Prognostic Relevance for Waldenström Macroglobulinemia |
NCI: Berndt, Sonja I.; Jianxin, Shi Dana-Farber Cancer Institute: Treon, Steven P.; Hunter, Zachary Mayo Clinic: Mondello, Patrizia Sloan-Kettering Institute for Cancer Research: Joseph, Vijai International Agency for Research on Cancer: : McKay, James |
| Developing a Theranostic Agent for Multiple Myeloma Based on a BCMA-targeted Nanobody |
NCI: Choyke, Peter; Hill, Elizabeth; Young, Ryan University of Miami: Landgren, Ola; Kazandjian, Dickran |
| Does vaginal microbiome seeding of cesarean section delivered infants reduce the risk of obesity and atopic disease? |
NIAID: Hourigan, Suchitra; Guerrerio, Pamela NIDDK: Courville, Amber; Chung, Stephanie Therese; Chen, Kong Y |
| Using Artificial Intelligence and Radiomics to Predict Hepatocellular Carcinoma Risk in Cirrhosis Patients |
NIDDK: Hsu, Christine; Liang, Jake NCI: Turkbey, Baris Ismail University of Pennsylvania: Hoteit, Marrouf Thomas Jefferson University: Kalman, Richard |
| Translational Approaches Unraveling Birdshot Chorioretinopathy Disease Etiology and Advancing Therapeutic Innovations |
NEI: Mattapallil, Mary; Caspi, Rachel |
| Translating Activity of Bitopertin in Diamond Blackfan anemia syndrome to show therapeutic potential in Myelodysplastic Syndrome patients |
NCI: McGraw, Kathy; Taylor, Naomi NHLBI: Young, David Jose |
| New biologics to treat asthma in inner city populations sensitized to rodents |
NEIHS: Mueller, Geoffrey Mass General: Patil, Sarita |
| The role of sandfly bites on regulating skin oxygenation and immune cell function in mice and humans: implications for leishmaniasis severity |
NIAID: Oliveria, Luiz; Marques, Adriana Ohio State University: Novais, Fernanda |
| Nanobody-based CAR targeting of an endogenous retroviral envelope for the treatment of glioblastoma |
NCI: Taylor, Naomi; Altan-Bonnet, Gregoire Yves NINDS: Nath, Avindra Sylvester Comprehensive Cancer Center: Shah, Ashish Harish |
| Developing Red Cell-specific Spleen Tyrosine Kinase (SYK) Inhibitors for Treating Sickle Cell Disease |
NHLBI: Thein, Swee Lay NIDDK: Eaton, William A. Purdue University: Low, Philip Stewart; Srinivasarao, Madduri |
AIDS CATEGORY: Project funded by Office of AIDS Research (OAR)
| Project | Institute or Institution/Investigators |
|---|---|
| Treatment of HIV Infection using an anti-HIV antibody-like molecule eCD4-Ig |
NIAID: CChun, Tae-Wook; Susan Moir Emmune, Inc.: : Alpert, Michael University of Maryland School of Medicin: Heredia, Alonso |
| Development of Novel HIV DNA-nanoparticle Vaccine for Clinical Application |
NCI: Felber, Barbara; Maldarelli, Frank NIAID: Eller, Michael; Pensiero, Michael Frederick National Laboratory of Cancer: Deleage, Claire HDT Bio: Reed, Steven Ragon Institute of NGH, MIT, and Harvard: Gaiha, Gaurav |
DIETARY SUPPLEMENTS CATEGORY: Project funded by Office of Dietary Supplements (ODS)
| Project | Institute or Institution/Investigators |
|---|---|
| Combining nicotinamide riboside with ketogenic diet to prevent fatty liver disease |
NIDDK: Hengist, Aaron; Chung, Stephanie Therese CC: Maki, Katherine Anne NCI: Qi, Ming; Gonzalez, Frank J. |
| Antioxidant Therapy for Smith-Lemli-Opitz Syndrome |
NICHD: Porter, Forbes; Rahhal, Samar D.; Labor, Desiree NCATS: Ottinger, Elizabeth NIMH: Thurm, Audrey; Farmer, Cristan University of Illinois: Cologna, Stephanie; Mohr, Justin |
| Effect of dietary dihomo-gamma-linolenic acid on inflammation-related conditions |
NHLBI: Remaley, Alan; Amar, Marcelo; Yang, Zhihong NIAID: Schwarz, Benjamin University of California: Zivkovic, Angela M. |
WOMEN’S HEALTH CATEGORY: Project funded by Office of Research on Women’s Health (ORWH)
| Project | Institute or Institution/Investigators |
|---|---|
| Ultrasound for Dynamic TMJ Imaging: MRI-Guided |
NIDCR: Lee, Janice; Almpani, Konstantinia; Venkateswaran, Vidhya |
| Structure Labeling and AI-Assisted Image Acquisition |
CC: Alter, Katharine E.; Biassou, Nadia Clemson University: Yao, Hai; Sun, Shuchun Florida State University: Slate, Elizabeth University of South Carolina: Jensen, Jens |
BEHAVIORAL & SOCIAL SCIENCES CATEGORY: Project funded by Office of Behavioral & Social Sciences Research (OBSSR)
| Project | Institute or Institution/Investigators |
|---|---|
| Investigating the role of effort before a meal on food intake and obesogenic food behaviors |
CC: Farmer, Nicole NIDDK: Darcey, Valerie Washington University in St. Louis: Kravitz, Alexxai |
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