U.S. Department of Health & Human
Services
OFFICE OF CLINICAL RESEARCH EDUCATION AND COLLABORATION OUTREACH
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Bench-to-Bedside and Back Program (BtB)
Current Awards
2024 Bench-to-Bedside and Back Program (BtB) Funded Projects
Office of Clinical Research Education and Collaboration Outreach (OCRECO): Projects Funded by Bench-to Bedside Program Funds
| Project | Institute or Institution/Investigators |
|---|---|
| Soluble Adenylyl Cyclase Inhibition in Pulmonary Arterial Hypertension |
NHLBI: Hersi, Kadija; Elinoff, Jason CC: Danner, Robert University of Illinois: Minshall, Richard; Oliveira, Suellen Darc dos Santos Johns Hopkins University: Hassoun, Paul; Mathai, Stephen |
| Immunoproteomic Profiling of Venovenous Extracorporeal Membrane Oxygenation |
NHLBI: Kanth, Shreya; Torabi-Parizi, Parizad University of Maryland: Rabin, Joseph; Taylor, Bradley; Scalea, Thomas; Griffith, Bartley |
| Contribution of Inflammation to the Pathogenesis of RUNX1-FPDMM |
NHGRI: Liu, Paul NHLBI: Dunbar, Cynthia; Young, David Oregon Health & Science University: Agarwal, Anupriya Northwestern University: Godley, Lucy |
| Defining Mechanisms Linking Ultra-Processed Foods to Inflammation |
CC: Maki, Katherine NIDDK: Hall, Kevin NHLBI: Sack, Michael; Klein, Rachael |
| Mechanistic Insights to New Drugs for Treating Sickle Cell Disease |
NHLBI: Mizuno, Naoko; Biertuempfel, Christian; Thein, Swee-Lay NIDDK: Eaton, William |
| Environment, genes, and sex modulate neuro-reproductive activity |
NIEHS: Shaw, Natalie; Archer, Trevor NCATS: Jovanovic, Vukasin; Tristan, Carlos; Xia, Menhang; Yang, Shu Colorado State University: Nestor, Casey |
| Acamprosate in C9orf72-related ALS and FTD (ACALS) |
NIA: Traynor, Bryan NINDS: Kwan, Justin; Nath, Avindra; Reoma, Lauren |
| Metformin eye drops: topical delivery as a potential treatment of AMD |
NEI: Sharma, Ruchi; Bharti, Kapil; Chew, Emily; Keenan, Tiarnan; Farnoodian Tedrick, Mitra Johns Hopkins University Wilmer Eye Institute: Sinha, Debasish |
| Development of a novel multi-agent targeted therapy for multiple myeloma |
NCI: Young, Ryan; Young, Elizabeth NCATS: Thomas, Craig; Ceribelli, Michele Mayo Clinic Arizona: Chesi, Marta; Bergsagel, Leif |
AIDS CATEGORY: Project funded by Office of AIDS Research (OAR)
| Project | Institute or Institution/Investigators |
|---|---|
| Intensification of antiviral therapy with lenacapavir in people with HIV |
NIAID: Chun, Tae-Wook; Sneller, Michael; Moir, Susan NCI: Maldarelli, Frank University of Pittsburgh: Devanathan, Aaron Sriram |
| Non-canonical integrase strand transfer inhibitor resistance pathways |
NCI: Freed, Eric University of Pittsburgh: Parikh, Urvi |
| Early metabolic effects of Dolutegravir or Tenofovir Alafenamide |
CC: Kuruppu, Janaki; Kovacs, Joseph NCI: Figg, William Douglas NIAID: Sereti, Irini NIDDK: Chen, Kong |
| Biomarkers and biology of aging in people with HIV |
NIAID: Sereti, Irini; Brenchley, Jason; Epling, Brian University of Pittsburgh: Pandrea, Ivona |
DIETARY SUPPLEMENTS CATEGORY: Project funded by Office of Dietary Supplements (ODS)
| Project | Institute or Institution/Investigators |
|---|---|
| Role of Blautia wexlerae in GLP1 Secretion after Dietary Fatty Acids |
NICHD: Yanovski, Jack; Brady, Sheila CC: Turner, Sara; Yang, Shanna NIAID: Hourigan, Suchitra NIDDK: Chen, Kong Boston Children's Hospital: Zhang, Yanjia Jason |
WOMEN’S HEALTH CATEGORY: Project Co-funded by Office of Research on Women’s Health (ORWH) and the Office of Clinical Research Education and Collaboration Outreach (OCRECO)
| Project | Institute or Institution/Investigators |
|---|---|
| A pilot study for treating chronic fatigue syndrome (ME/CFS) |
NHLBI: Hwang, Paul; Wang, Ping-yuan NINDS: Bedard, Patrick; Nath, Avindra; Walitt, Brian |
| Role of Eosinophils in Spontaneous Coronary Artery Disease Pathogenesis |
NIAID: Klion, Amy; Khoury, Paneez; Fay, Michael NCI: Kleiner, David NHLBI: Bandettini, Patricia New York University: Fishman, Glenn |
| Deep immunophenotyping of breast milk and maternal immunity over lactation |
NIAID: Manthiram, Kalpana; Corral, Dan; Hourigan, Suchitra; Schwartzberg, Pamela; Xu, Qin NHLBI: Altan-Bonnet, Nihal |
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