U.S. Department of Health & Human Services
OFFICE OF CLINICAL RESEARCH EDUCATION AND COLLABORATION OUTREACH
- Clinical Center Director's Award for 2015 in the Strategic Initiatives category. The award was granted for implementing evaluation of key strategic programs and initiatives such as opening the Clinical Center for extramural.
- NIAMS Director’s award 2005
- NIH Award of Merit, 1991
- UMUC’s Upsilon Phi Delta (UPD) Honor Society
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Staff Profile
Hana Smith, MS
Biography
Hana Smith is a Program Director in the NIH Office of Clinical Research Education and Collaboration Outreach. In this role, she oversees all aspects of these program including and not limited to : the scientific review panel, coordination, and implementation of research activities. Hana has been at the NIH as a senior research chemist for over twenty five years. During that time, she developed expertise in multiple biomedical research disciplines and methodologies. Here research focused on conducting studies to examine the function of joints using cellular, genetics and molecular approaches, in addition to applying cell-based tissue engineering for cartilage replacement using adult stem cells. Other research was conducted on the structure of immunoglobulins and their interaction with antigens and with cell surface receptors. She also, served as a reviewer for manuscripts and provided advice and edits before submitting for peer reviewed journals. Hana published numerous manuscripts as the lead author and others as a collaborator.
She received a Bachelor's of Science in Chemistry and Biology from Boston University in Massachusetts and a Master's of Science in Health Care Administration from the University of Maryland. She also attended the Johns Hopkins University School of Hygiene & Public Health.
Honors and Awards
Selected Publications
Haleem‐Smith, Hana, Raul Calderon, Yingjie Song, Rocky S. Tuan, and Faye H. Chen. "Cartilage oligomeric matrix protein enhances matrix assembly during chondrogenesis of human mesenchymal stem cells." Journal of cellular biochemistry 113, no. 4 (2012): 1245-1252.
Haleem‐Smith, Hana, Evan Argintar, Curtis Bush, Daniel Hampton, William F. Postma, Faye H. Chen, Todd Rimington, Joshua Lamb, and Rocky S. Tuan. "Biological responses of human mesenchymal stem cells to titanium wear debris particles." Journal of Orthopaedic Research 30, no. 6 (2012): 853-863.
Bergin, Patrick F., Jason D. Doppelt, Curtis J. Kephart, Michael T. Benke, James H. Graeter, Andrew S. Holmes, Hana Haleem-Smith, Rocky S. Tuan, and Anthony S. Unger. "Comparison of minimally invasive direct anterior versus posterior total hip arthroplasty based on inflammation and muscle damage markers." The Journal of Bone and Joint Surgery. American volume. 93, no. 15 (2011): 1392.
Pricola, Katie L., Nastaran Z. Kuhn, Hana Haleem‐Smith, Yingjie Song, and Rocky S. Tuan. "Interleukin‐6 maintains bone marrow‐derived mesenchymal stem cell stemness by an ERK1/2‐dependent mechanism." Journal of cellular biochemistry 108, no. 3 (2009): 577-588.
Okafor, Chukwuka C., Hana Haleem‐Smith, Patrice Laqueriere, Paul A. Manner, and Rocky S. Tuan. "Particulate endocytosis mediates biological responses of human mesenchymal stem cells to titanium wear debris." Journal of orthopaedic research 24, no. 3 (2006): 461-473.
Haleem-Smith, Hana, Assia Derfoul, Chukwuka Okafor, Richard Tuli, Douglas Olsen, David J. Hall, and Rocky S. Tuan. "Optimization of high-efficiency transfection of adult human mesenchymal stem cells in vitro." Molecular biotechnology 30, no. 1 (2005): 9-19.
Tuli, Richard, Suraj Tuli, Sumon Nandi, Mark L. Wang, Peter G. Alexander, Hana Haleem‐Smith, William J. Hozack, Paul A. Manner, Keith G. Danielson, and Rocky S. Tuan. "Characterization of multipotential mesenchymal progenitor cells derived from human trabecular bone." Stem Cells 21, no. 6 (2003): 681-693.
Metzger, Henry, Santa Eglite, Hana Haleem-Smith, Ilona Reischl, and Chikako Torigoe. "Quantitative aspects of signal transduction by the receptor with high affinity for IgE." Molecular immunology38, no. 16 (2002): 1207-1211.
Vonakis, Becky M., Hana Haleem-Smith, Peter Benjamin, and Henry Metzger. "Interaction between the unphosphorylated receptor with high affinity for IgE and Lyn kinase." Journal of Biological Chemistry 276, no. 2 (2001): 1041-1050.
Liu, Zhao-Jun, Hana Haleem-Smith, Huaxian Chen, and Henry Metzger. "Unexpected signals in a system subject to kinetic proofreading." Proceedings of the National Academy of Sciences98, no. 13 (2001): 7289-7294.
Metzger, Henry, Huaxian Chen, Byron Goldstein, Hana Haleem-Smith, John K. Inman, Matthew Peirce, Chikako Torigoe, Becky Vonakis, and Carla Wofsy. "A quantitative approach to signal transduction." Immunology letters 68, no. 1 (1999): 53-57.
Metzger, Henry, Huaxian Chen, Byron Goldstein, Hana Haleem‐Smith, John Inman, Mathew Peirce, Chikako Torigoe, Becky Vonakis, and Carla Wofsy. "Signal transduction by FcɛRI: Analysis of the early molecular events." Allergology International 48, no. 3 (1999): 161-169.
Vonakis, B. M., Haleem-Smith, H., Benjamin, P. S., & Metzger, H. (1998). Structural basis for the interaction of lyn kinase with the unphosphorylated high affinity receptor for IgE Fc (RI). FASEB Journal, 12(8).
Vonakis, Becky M., Huaxian Chen, Hana Haleem-Smith, and Henry Metzger. "The unique domain as the site on Lyn kinase for its constitutive association with the high affinity receptor for IgE." Journal of Biological Chemistry 272, no. 38 (1997): 24072-24080.
Haleem-Smith, Hana, En-Yuh Chang, Zoltan Szallasi, Peter M. Blumberg, and Juan Rivera. "Tyrosine phosphorylation of protein kinase C-delta in response to the activation of the high-affinity receptor for immunoglobulin E modifies its substrate recognition." Proceedings of the National Academy of Sciences 92, no. 20 (1995): 9112-9116.
Wujek, Jerome R., Hana Haleem-Smith, Yoshihiko Yamada, Robert Lipsky, Yueh Tze Lan, and Ernst Freese. "Evidence that the B2 chain of laminin is responsible for the neurite outgrowth-promoting activity of astrocyte extracellular matrix." Developmental Brain Research 55, no. 2 (1990): 237-247.
Date page last updated: 7/28/22
Hana Smith
Program Director, Bench to Bedside and RASCL Awards
Email: [email protected]
Phone:
301-402-6313
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